The Simpsons
The Simpsons follows Homer, a nuclear plant worker, and his quirky family in Springfield. His wife Marge, kids Bart, Lisa, and Maggie, along with colorful neighbors like Ned Flanders and Moe, make for comedic adventures.
Family Guy
Family Guy follows the Griffin family in Quahog, R.I. Peter and Lois raise their kids Meg, Chris, and genius baby Stewie, while their talking dog Brian navigates life and keeps Stewie in check.
Regular Show
Follows best buds Mordecai and Rigby, a bluejay and a racoon, and their misadventures. Employed as groundskeepers, their daily lives are anything but regular.